Full Time
Posted 2 months ago

COMPASS Pathways plc is a mental health care company dedicated to accelerating patient access to evidence-based innovation in mental health (https://compasspathways.com/). Our first major initiative is developing psilocybin therapy for patients with treatment-resistant depression, using our COMP360 psilocybin in conjunction with psychological support; we are in the final stages of a large-scale, international phase IIb clinical trial. At the same time, our Preclinical team is busy building a comprehensive R&D portfolio with new compounds and indications, focused on our Discovery Center in the US, and in collaboration with partners all over the world.

Preclinical research is fundamental to the COMPASS mission and one of our key investment areas. Our multi-disciplinary preclinical team brings together a range of subject matter experts with extensive academic and industrial experience to deliver innovation at the earliest stages of the drug discovery and development process.

In addition to providing the foundational science to support our investigational COMP360 psilocybin therapy on its clinical journey, we are committed to building a broad and sustainable portfolio of assets, eg through our Discovery Center, that will transform how mental health care is delivered. We collaborate with academics and partners at the cutting edge of science, and have a bold scientific vision to embrace translational and integrative neuroscience approaches that will move us far beyond traditional approaches to psychiatric drug discovery. 

We currently have an open position in the R&D team for a (Senior) Research Scientist with a background in next-generation sequencing and molecular biology.

Location: United Kingdom. 

Reports to: Senior Research Scientist, Cell and Molecular biology.

Roles and responsibilities:

Main responsibilities include (but are not limited to):

  • Independently design and develop preclinical NGS/molecular biology studies
  • Identification of new technical developments and trends to help answer complex research questions
  • Management of research projects through interactions with internal and external stakeholders (eg CROs or academic scientists)
  • Analysis, interpretation and recording of experimental results generating study reports in a concise and timely manner
  • Ensuring data management remains in line with good research practices
  • Presenting study results to internal and external stakeholders
  • Conducting literature searches and report findings to communicate findings
  • Participating in external scientific events
  • Providing scientific input and develop NGS approaches for ongoing research and novel target drug discovery efforts

NOTE: responsibilities do not involve running any experiments/wet lab work.


  • PhD in neuroscience, biological sciences, molecular biology or similar
  • Experience designing in vitro and/or in vivo studies to address key scientific questions
  • Experience and knowledge of NGS methods (RNAseq, scRNAseq, WES)
  • Experience of bioinformatics analysis and handling of NGS raw data
  • Independent, motivated with strong problem-solving skills
  • Excellent organisational, planning, teamworking and communication skills (verbal and written)

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